產(chǎn)品編號 | D58195 |
英文名稱 | BRD6989 |
CAS | 642008-81-9 |
檢測分子量 | 264.33 |
保存條件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
產(chǎn)品介紹 |
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM. |