產(chǎn)品編號(hào) | IHC0330H |
英文名稱 | Human RPS19 Ready-To-Use IHC Kit |
中文名稱 | 人S19核糖體蛋白即用型免疫組化試劑盒 |
別 名 | DBA1, Dsk3, S19, 40S ribosomal protein S19, DBA, ribosomal protein S19, RPS19 |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia, a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human brain tissue slide using IHC0330H (Human RPS19 Kit).
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