產(chǎn)品編號 |
IHC0336M |
英文名稱 |
Mouse APAF1 Ready-To-Use IHC Kit
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中文名稱 |
小鼠凋亡蛋白活性因子-1即用型免疫組化試劑盒 |
別 名 |
6230400I06Rik, APAF-1, Apaf1l, fog, mKIAA0413, APAF 1, APAF1, CED4, DKFZp781B1145, KIAA0413 |
保存條件 |
Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
APAF1 gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
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產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded mouse heart tissue slide using IHC0336M (Mouse APAF1 Kit).
Immunohistochemical analysis of paraffin embedded mouse spleen tissue slide using IHC0336M (Mouse APAF1 Kit).
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