產(chǎn)品編號(hào) | IHC0339H |
英文名稱 | Human PIK3C3 Ready-To-Use IHC Kit |
中文名稱 | 人磷脂酰肌醇激酶3催化亞單位3即用型免疫組化試劑盒 |
別 名 | 5330434F23Rik, hVps34, PIK3C3, VPS34 |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. PIK3C3 phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes. PIK3C3 is involved in coupling nutrient signaling to mTOR and also plays a role in autophagy and intracellular trafficking. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes. |
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