產(chǎn)品編號(hào) | IHC0343H |
英文名稱(chēng) | Human Osteopontin Ready-To-Use IHC Kit |
中文名稱(chēng) | 人骨橋蛋白/分泌型磷蛋白1即用型免疫組化試劑盒 |
別 名 | BNSP, BSPI, ETA-1, OPN, PSEC0156, SPP1, Bone sialoprotein 1, BSP I, Early T lymphocyte activation 1, ETA 1, ETA1, MGC110940, Nephropontin, osteopontin, Secreted phosphoprotein 1, SPP 1, SPP-1, SPP1/CALPHA1 fusion, Urinary stone protein, Uropontin |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D. |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human pancreatic cancer tissue slide using IHC0343H (Human Osteopontin Kit).
Immunohistochemical analysis of paraffin embedded human pancreas tissue slide using IHC0343H (Human Osteopontin Kit).
Immunohistochemical analysis of paraffin embedded human kidney tissue slide using IHC0343H (Human Osteopontin Kit).
Immunohistochemical analysis of paraffin embedded human brain tissue slide using IHC0343H (Human Osteopontin Kit).
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