| 產(chǎn)品編號(hào) | IHC0356H |
| 英文名稱(chēng) | Human Periostin Ready-To-Use IHC Kit |
| 中文名稱(chēng) | 人成骨細(xì)胞特異性因子2即用型免疫組化試劑盒 |
| 別 名 | A630052E07Rik, AI747096, OSF-2, OSF2, PDLPOSTN, peri, PLF, PN, POSTN, Osteoblast-specific factor 2, Periostin |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor beta 1(TGF beta 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain. |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human stomach tissue slide using IHC0356H (Human Periostin Kit).
Immunohistochemical analysis of paraffin embedded human mammary gland tissue slide using IHC0356H (Human Periostin Kit).
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Immunohistochemical analysis of paraffin embedded human colon tissue slide using IHC0356H (Human Periostin Kit).
Immunohistochemical analysis of paraffin embedded human lung cancer tissue slide using IHC0356H (Human Periostin Kit).
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