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Rabbit Anti-TSPY1/AP Conjugated antibody (bs-6607R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-6607R-AP
英文名稱1 Rabbit Anti-TSPY1/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的睪丸特異定蛋白質(zhì)編碼Y1抗體
別    名 DYS14; pJA 923; pJA923; Testis specific protein Y linked 1; Testis specific Y encoded protein 1; TSPY 1; TSPY; TSPY1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  發(fā)育生物學(xué)  染色質(zhì)和核信號(hào)  干細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TSPY1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The function of this protein is unknown. TSPY genes are located on the Y-chromosome of several mammalian species. TSPY encodes a testis-specific protein 1, which probably acts as nucleosome-binding transcription factor. Homology with the SET/NAP/DENTT oncogene family suggest a role in spermatogonic cell division and seminal oncogenesis.

Function:
May be involved in sperm differentiation and proliferation.

Subcellular Location:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also found in nucleus.

Tissue Specificity:
Specifically expressed in testicular tissues. Isoform 1 and isoform 2 are expressed in spermatogonia and spermatocytes. Found in early testicular carcinoma in situ, spermatogonial cells in testicular tissues of 46,X,Y female and in prostate cancer cell lines.

Post-translational modifications:
Phosphorylated.

Similarity:
Belongs to the nucleosome assembly protein (NAP) family.

Database links:
 

UniProtKB/Swiss-Prot: Q01534.4



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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