| 產(chǎn)品編號 | bs-1389R-BF488 |
| 英文名稱1 | Rabbit Anti-Cyclin G/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的周期素G抗體 |
| 別 名 | CCNG 1; CCNG; CCNG1; CYCG1; Cyclin G; CCNG1_HUMAN; Cyclin-G; Cyclin G1; CyclinG1; Cyclin-G1. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 染色質(zhì)和核信號 細(xì)胞周期蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Cyclin G |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor. Cyclin G2 shares 53% amino acid sequence identity with cyclin G1. Peak expression of cyclin G2 is seen in late S phase, as opposed to cyclin G1 expression, which is constitutive. Function: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity). Subcellular Location: Nucleus. DNA replication foci after DNA damage. Tissue Specificity: High levels in skeletal muscle, ovary, kidney and colon. Similarity: Belongs to the cyclin family. Cyclin G subfamily. Database links: Entrez Gene: 900 Human Omim: 601578 Human SwissProt: P51959 Human Unigene: 79101 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Cyclin G的生物功能還沒有完全清楚，他是細(xì)胞周期蛋白家族中近來發(fā)現(xiàn)的新成員，也是已知的唯一受到腫瘤抑制基因p53調(diào)控的細(xì)胞周期蛋白。 近年來經(jīng)研究發(fā)現(xiàn)，Cyclin G可能有促進細(xì)胞增長的作用，在細(xì)胞增殖和神經(jīng)再生中的可能起到一定的作用。 |
