来一水AV@lysav|亚洲AV无码片VR一区二区三区 |国产亚洲精久久久久久无码|视色4se成人午夜精品久久

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
俺去俺来也在线www色官网|性国产SE╳O色欲A片欢迎观看
Rabbit Anti-CD130/PE Conjugated antibody (bs-1459R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1459R-PE
英文名稱1 Rabbit Anti-CD130/PE Conjugated antibody
中文名稱 PE標(biāo)記的白細(xì)胞介素6受體β/CD130抗體
別    名 IL-6R Beta; Interleukin-6 receptor subunit beta; IL-6R-beta; Interleukin-6 signal transducer; Membrane glycoprotein 130; gp130; CDw130; Oncostatin-M receptor subunit alpha; CD_antigen; CD130; GP130 RAPS; gp130 transducer chain; GP130-RAPS; IL6 ST; IL6R-beta; IL6ST.IL6R-beta.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 99kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IL6R beta
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Function:
Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development. The type I OSM receptor is capable of transducing OSM-specific signaling events.

Subunit:
Interacts with INPP5D/SHIP1. Forms heterodimers composed of LIPR and IL6ST (type I OSM receptor). Also forms heterodimers composed of OSMR and IL6ST (type II OSM receptor). Homodimer. The homodimer binds two molecules of herpes virus IL6. Component of a hexamer of two molecules each of IL6, IL6R and IL6ST. Interacts with HCK.

Subcellular Location:
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.

Tissue Specificity:
Found in all the tissues and cell lines examined. Expression not restricted to IL6 responsive cells.

Post-translational modifications:
Phosphorylation of Ser-782 down-regulates cell surface expression.
Heavily N-glycosylated.

Similarity:
Belongs to the type I cytokine receptor family. Type 2 subfamily.
Contains 5 fibronectin type-III domains.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 3572 Human

Entrez Gene: 16195 Mouse

Omim: 600694 Human

SwissProt: P40189 Human

SwissProt: Q00560 Mouse

Unigene: 532082 Human

Unigene: 706627 Human

Unigene: 4364 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.73327.net 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
久久精品国产av一区二区三区 | 激情都市| 亚洲午夜精品久久久久久浪潮| 无码一区二区三区| 亚洲高清欧美日韩一区二区三区| FREEXX性黑人大战欧美视频| 又湿又紧又大又爽A视频国产| 欧美一区二区三区不卡在线观看 | 亚洲阿v国产精品日韩| 久久久久久久国产精品免费| 越南女与动交ZOZ0Z| 漂亮人妻被黑人久久精品噜噜噜激激| 久久久久无码精品国产| 天天躁久久躁中文字字幕| 久久高清内射无套| 新岳乱合集500系列| 性做爰高清视频在线观看视频| 大屁股熟女一区二区三区| 国产精品不卡在线免费观看| 欧美日韩国产免费看| 后入视频在线播放天天干| 青青草在线视频vip华人www8dashunet | 在线偷着国产精选视频| 亚洲色大成网站WWW| 亚洲成A∨人在线播放欧美| 三年片在线观看免费大全爱奇艺| 亚洲AV无一区二区三区| 精品AV无码国产一区二区| 久久久久99精品成人免费| 亚洲一区二区三区视频在线播放| 日韩精品一区二区三区含羞含羞草 | 在线精品日韩一区二区三| 欧美va精品亚洲va精品| 亚洲精品乱码久久久久久自慰 | 少妇荡乳情欲办公室456视频| 麻豆国内剧情AV在线素人搭讪| 黑龙江发廊按摩老熟女| 国产亚洲精品久久久一区| 亚洲av在线观看| 好爽又高潮了毛片免费下载| av超碰100免费|