| 產品編號 |
bs-1470R-PE-Cy5.5 |
| 英文名稱1 |
Rabbit Anti-CD82/PE-Cy5.5 Conjugated antibody
|
| 中文名稱 |
PE-Cy5.5標記的腫瘤轉移抑制蛋白1抗體 |
| 別 名 |
4F9; Antigen detected by monoclonal and antibody IA4; C33; C33 antigen; CD 82; CD82 antigen; CD82 molecule; GR 15; GR15; IA 4; IA4; Inducible membrane protein; Inducible membrane protein R2; KAI 1; KAI1; Kangai 1; Kangai1; Metastasis suppressor Kangai 1; Metastasis suppressor Kangai1; R2 leukocyte antigen; CD82_HUMAN.
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| 規(guī)格價格 |
100ul/2980元
購買 大包裝/詢價 |
| 說 明 書 |
100ul
|
| 研究領域 |
腫瘤 免疫學 信號轉導 轉錄調節(jié)因子 細胞表面分子 細胞類型標志物 t-淋巴細胞 |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應 |
(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
|
| 產品應用 |
IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
29kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human CD82 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產品介紹 |
background:
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.
Subunit:
Interacts directly with IGSF8.
Subcellular Location:
Membrane.
Tissue Specificity:
Lymphoid specific.
Similarity:
Belongs to the tetraspanin (TM4SF) family.
Database links:
Entrez Gene: 3732 Human
Entrez Gene: 12521 Mouse
Entrez Gene: 83628 Rat
Omim: 600623 Human
SwissProt: P27701 Human
SwissProt: P40237 Mouse
SwissProt: O70352 Rat
Unigene: 527778 Human
Unigene: 4261 Mouse
Unigene: 3022 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
信號傳導（Signaling Intermediates）
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