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Rabbit Anti-Upstream Binding Protein 1/Gold Conjugated antibody (bs-6730R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術支持:techsupport@73327.net
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-6730R-Gold
英文名稱1 Rabbit Anti-Upstream Binding Protein 1/Gold Conjugated antibody
中文名稱 膠體金標記的上游結(jié)合蛋白1抗體
別    名 LBP 1a; Cp2b; DKFZp686L1745; LBP 1a; LBP 1B; LBP1; LBP1A; LBP1B; NF2d9; Upstream binding protein 1; Transcription factor LBP-1; UBIP1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Upstream Binding Protein 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

Function:
UBP1 is an important SF1 independent transcriptional activator stimulating P450scc expression in human placental JEG 3 cells.

Subunit:
Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in adrenal tissue, JEG-3, NCI-H295A, HepG2 and HeLa cell lines.

Similarity:
Belongs to the grh/CP2 family. CP2 subfamily.

Database links:

Entrez Gene: 7342 Human

Entrez Gene: 22221 Mouse

Entrez Gene: 301038 Rat

Omim: 609784 Human

SwissProt: Q86Y57 Human

SwissProt: Q9NZI7 Human

SwissProt: Q60786 Mouse

SwissProt: Q811S7 Mouse

SwissProt: Q8BH21 Mouse

Unigene: 118041 Human

Unigene: 729120 Human

Unigene: 28052 Mouse

Unigene: 386808 Mouse

Unigene: 15705 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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