来一水AV@lysav|亚洲AV无码片VR一区二区三区 |国产亚洲精久久久久久无码|视色4se成人午夜精品久久

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
亚洲熟女一区二区三区|青青青在线香蕉免费国产|欧洲成人午夜精品无码区久久
Rabbit Anti-TIMP-1/Cy3 Conjugated antibody (bs-4600R-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-4600R-Cy3
英文名稱1 Rabbit Anti-TIMP-1/Cy3 Conjugated antibody
中文名稱 Cy3標(biāo)記的金屬蛋白酶組織抑制因子-1抗體
別    名 Clgi; Collagenase inhibitor; EPA; EPO; Erythroid Potentiating Activity; Fibroblast collagenase inhibitor; FLJ90373; HC; Human Collagenase Inhibitor; Metalloproteinase inhibitor 1; Metalloproteinase inhibitor 1 precursor; OTTHUMP00000023214; TIMP 1; TIMP; TIMP metallopeptidase inhibitor 1; TIMP1 protein; Tissue Inhibitor of Metalloproteinase 1; Tissue inhibitor of metalloproteinases; Ttissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor.   
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞凋亡  生長因子和激素  激酶和磷酸酶  合成與降解  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TIMP-1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq].

Function:
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14.

Subcellular Location:
Secreted.

Post-translational modifications:
The activity of TIMP1 is dependent on the presence of disulfide bonds.

Similarity:
Belongs to the protease inhibitor I35 (TIMP) family.
Contains 1 NTR domain.

Database links:

Entrez Gene: 7076 Human

Entrez Gene: 21857 Mouse

Omim: 305370 Human

SwissProt: P01033 Human

SwissProt: P12032 Mouse

Unigene: 522632 Human

Unigene: 8245 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

TIMP1是基質(zhì)金屬蛋白酶的抑制酶,其功能與MMP相反,能抑制腫瘤細(xì)胞的浸潤和轉(zhuǎn)移,主要用于各種惡性腫瘤如乳腺癌等的研究。TIMP-1是一種28kDa的糖蛋白,主要分泌細(xì)胞為多種結(jié)締組織細(xì)胞,被認(rèn)為是組織中MMPs活性的主要調(diào)節(jié)者,它可以和MMPs家族成員以共價(jià)鍵方式形成1:1的復(fù)合物,從而發(fā)揮其抑制作用。在正常生理?xiàng)l件下,MMPs和TIMPs之間的平衡狀態(tài)是維持細(xì)胞外基質(zhì)正常狀態(tài)所必需的,一旦它們之間的比例失調(diào),就會(huì)造成一系列的病理狀態(tài)。
版權(quán)所有 2004-2026 www.73327.net 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
JAPANESEHD熟女熟妇伦| 国产女人AAA级久久久级| 丰满的女人一区二区三区| 免费国偷自产拍精品视频| 一本色道无码道DVD在线观看| 亚洲高清精品一区二区三区| 国产精品自在欧美一区| 人人妻人人藻人人爽欧美一区| 被背叛的田川的忧郁| 公交车上~嗯啊被高潮| 国产精品无码V在线观看| 亚洲成色精品一区二区| 久久久国产精品免费A片3D| 青青草原综合久久大伊人精品| 久久中文字幕一区二区| 亚洲午夜福利院在线观看| 国产亚洲精品精华液| 国产美女一级A做爰在线看| 日韩精品无码一本二本三本色| 中文字字幕在线中文无码 | 高清无码在线观看网站| 少妇精品久久久久久0000| 中文乱码人妻系列一区二区| 免费A级毛片AV无码| 日本精品二区三区四区| 无码人妻精品一区二区三区久久久| 伦理精品一区二区三区| 亚洲3d成人动漫在线观看| WWW夜插内射视频网站| 特黄三级又爽又粗又大| 欧美日韩成人在线网| 国产丝袜无码一区二区视频| 亚洲日韩精品一区二区三区| 国产日韩欧美精品在线| 成人毛片18女人毛片免费看| 91福利在线精品国产| 日韩欧美中文久久久| 日本乱偷人妻中文字幕在线 | 亚洲精品乱码久久久久久按摩| 青青青视频香蕉在线观看视频 | 亚洲欧美v视色一区二区|