来一水AV@lysav|亚洲AV无码片VR一区二区三区 |国产亚洲精久久久久久无码|视色4se成人午夜精品久久

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
激情五月色综合国产精品|国产偷抇久久精品A片69|精品亚洲一区二区三区四区五区
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Ephrin A1/Cy7 Conjugated antibody (bs-1763R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1763R-Cy7
英文名稱1 Rabbit Anti-Ephrin A1/Cy7 Conjugated antibody
中文名稱 Cy7標記的內(nèi)皮細胞受體蛋白酪氨酸激酶A/腫瘤壞死因子α誘導蛋白4抗體
別    名 B61; ECKLG; EFL 1; EFL1; EFNA 1; EFNA1; EFNA1_HUMAN; EPH related receptor tyrosine kinase ligand 1; EPH-related receptor tyrosine kinase ligand 1; Ephrin-A1; Ephrin-A1, secreted form; EphrinA1; EPLG 1; EPLG1; Immediate early response protein B61; LERK 1; LERK-1; LERK1; Ligand of eph related kinase 1; OTTHUMP00000033242; OTTHUMP00000033271; secreted form; TNF alpha-induced protein 4; TNFAIP 4; TNFAIP4; Tumor necrosis factor alpha induced protein 4; Tumor necrosis factor alpha-induced protein 4.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  心血管  神經(jīng)生物學  激酶和磷酸酶  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, )
產(chǎn)品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 19/22kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Ephrin A1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]

Function:
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cone and regulates dendritic spine morphogenesis.

Subunit:
Monomer. Homodimer. Forms heterodimers with EPHA2. Binds to the receptor tyrosine kinases EPHA2, EPHA3, EPHA4, EPHA5, EPHA6 and EPHA7. Also binds with low affinity to EPHA1.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.
Ephrin-A1, secreted form: Secreted.

Tissue Specificity:
Brain. Down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells (at protein level).

Post-translational modifications:
Undergoes proteolysis by a metalloprotease to give rise to a soluble monomeric form.

Similarity:
Belongs to the ephrin family.
Contains 1 ephrin RBD (ephrin receptor-binding) domain.

Database links:

Entrez Gene: 1942 Human

Entrez Gene: 13636 Mouse

Entrez Gene: 94268 Rat

Omim: 191164 Human

SwissProt: P20827 Human

SwissProt: P52793 Mouse

SwissProt: P97553 Rat

Unigene: 516664 Human

Unigene: 15675 Mouse

Unigene: 8427 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.73327.net 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
特级做A爰片毛片免费69| 欧美牲交a欧美牲交aⅴ无码| 久久AV无码精品人妻出轨| 欧美v日韩v国产综合| 亚洲综合有码中文字幕| 免费无码一线A片AAA片| 亚洲欧美另类精品久久| 日本亲近相奷中文字幕| 亚洲欧美另类在线日韩| 亚洲高清自有码中文字在线观看| 精品国产乱码久久久久久| 人与动人物A级毛片免费视频| 欧美熟妇丰满肥白大屁股免费视频 | 精品国产911在线观看| 国产放荡对白视频在线观看| 国内老熟妇对白XXXXHD| 精品熟人妻一区二区三区四区不卡| 亚洲熟妇av不卡一区二区三区| 国模精品一区二区三区| 久久国产精品无码网站| 特级毛片WWW| 久久亚洲精品成人AV无码网站| 99精品国产一区二区三| 无码精品人妻一区二区三区影院| 免费观看欧美一级黄片中文字幕| 久久综合色鬼综合色| 欧美日韩在线一二三区| 亚洲人成网站色7799| 性欧美大战久久久久久久久| 国产麻豆一精品一AV一免费| 亚洲一区精品无码色成人| 亚洲综合在线视频一区二区三区| 国产欧美日韩精品丝袜高跟鞋| 国产又粗又长又硬免费视频| 亚洲欧美另类在线日韩| 国产一区亚洲欧美在线| 日韩欧美中文久久久| 午夜人妻久久久久久| 14表妺好紧没带套18分钟| 亚洲av日韩综合精品国产| 久久久久久综合岛国免费观看|