来一水AV@lysav|亚洲AV无码片VR一区二区三区 |国产亚洲精久久久久久无码|视色4se成人午夜精品久久

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
精品久久久久中文字幕加勒比|日韩精品一区二区亚洲AV观看|无码人妻精品一区二区三区66
Rabbit Anti-KCNE1/AP Conjugated antibody (bs-9928R-AP)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@73327.net
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-9928R-AP
英文名稱1 Rabbit Anti-KCNE1/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的鉀離子通道蛋白家族成員1抗體
別    名 Delayed rectifier potassium channel subunit IsK; Human cardiac delayed rectifier potassium channel protein; IKs producing slow voltage gated potassium channel subunit beta Mink; ISK; JLNS 2; JLNS; JLNS2; KCNE 1; LQT 5; LQT5; Minimal potassium channel; MinK; Potassium voltage gated channel Isk related family member 1; Potassium voltage gated channel Isk related subfamily member 1; Potassium voltage gated channel subfamily E member 1; KCNE1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 心血管  神經(jīng)生物學(xué)  通道蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 15kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNE1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].

Function:
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).

Subunit:
Associates with KCNQ1/KVLQT1 and KCNH2/HERG.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed in heart, lung, kidney, testis, ovaries, small intestine, peripheral blood leukocytes. Not detected in pancreas, spleen, prostate and colon. Restrictively localized in the apical membrane portion of epithelial cells.

Post-translational modifications:
Phosphorylation inhibits the potassium current (By similarity).
N-glycosylation at Asn-26 occurs post-translationally, and requires prior cotranslational glycosylation at Asn-5.

DISEASE:
Defects in KCNE1 are the cause of Jervell and Lange-Nielsen syndrome type 2 (JLNS2) [MIM:612347]. JLNS2 is an autosomal recessive disorder characterized by congenital deafness, prolongation of the QT interval, syncopal attacks due to ventricular arrhythmias, and a high risk of sudden death.
Defects in KCNE1 are the cause of long QT syndrome type 5 (LQT5) [MIM:613695]. Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to exercise or emotional stress. KCNE1 mutants form channels that open slowly and close rapidly, thereby diminishing potassium currents.

Similarity:
Belongs to the potassium channel KCNE family.

Database links:

Entrez Gene: 3753 Human

Entrez Gene: 16509 Mouse

Entrez Gene: 397331 Pig

Entrez Gene: 25471 Rat

Omim: 176261 Human

SwissProt: P15382 Human

SwissProt: P23299 Mouse

SwissProt: Q9TUH9 Pig

SwissProt: P15383 Rat

Unigene: 121495 Human

Unigene: 299425 Mouse

Unigene: 9734 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.73327.net 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产一区二区精品久久| 爆乳熟妇乱操| 18无码粉嫩小泬无套在线观看| 七旬老人为满足需求| 噜噜噜久久午夜电影| 欧美成人在线视频| 无码久久精品国产亚洲AV影片| 久久久久噜噜噜亚洲熟女综合| 欧美老熟妇又粗又大| 国产男女无遮挡猛进猛出| 成人区人妻精品一区二区不卡视频| 性欧美XXXX| 五月丁香六月综合缴清无码 | 国内少妇偷人精品视频免费| 无码H黄肉3D动漫在线观看| 精品久久久久久久久久久久久久久久久| 四川丰满少妇被弄到高潮| 亚洲AV成人片无码| 中国美女撒尿TXXXX视频偷窥| 囗交姿势图3D效果展示图| 久久久久久久久波多野高潮 | 久久人人爽人人爽人人片AV高请| 亚洲AV无码久久寂寞少妇 | 青青草在线aH| av日韩在线观看一区二区三区| 最近中文字幕高清字幕MV| 波多野结衣电影| 日本一区二区精品在线| 国产一区二区不卡高清更新 日本v二区三区不卡无 | 91精品国产高清久久久久 | 日本午夜精品福利视频| 无套中出丰满人妻无码| 少妇被多人C夜夜爽爽AV| 亚洲日韩精品无码AV海量| 中文字幕2017| 粉嫩一区二区三区性色av| 亚洲综合精品国产av| 国产精品久久久久久三级精品| 又大又粗又爽免费视频A片| 亚洲一区二区三区视频在线播放| 国产99久久九九精品无码|