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Rabbit Anti-Nuclear Pore Complex Proteins/Nup107/Gold Conjugated antibody (bs-11678R-Gold)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@73327.net
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說(shuō) 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11678R-Gold
英文名稱1 Rabbit Anti-Nuclear Pore Complex Proteins/Nup107/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的核孔復(fù)合體蛋白抗體
別    名 107 kDa nucleoporin; NPC proteins; NU107_HUMAN; Nuclear pore complex protein Nup107; Nucleoporin 107kDa; Nucleoporin Nup107; NUP 107; NUP 84; NUP107; NUP153; NUP155; NUP84; NUP98.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 染色質(zhì)和核信號(hào)  神經(jīng)生物學(xué)  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Pig, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 106kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nuclear Pore Complex Proteins (501-600aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

Function:
Essential component of nuclear pore complex. Required for the assembly of peripheral proteins into the nuclear pore complex.

Subunit:
Forms part of the Nup160 subcomplex in the nuclear pore which is composed of Nup160, Nup133, Nup107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and Nup153 to the nucleus.

Subcellular Location:
Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the nuclear pore. During mitosis, localizes to the kinetochores.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the nucleoporin Nup84/Nup107 family.

Database links:

Entrez Gene: 57122 Human

Entrez Gene: 103468 Mouse

Entrez Gene: 116555 Rat

Omim: 607617 Human

SwissProt: P57740 Human

SwissProt: Q3TT06 Mouse

SwissProt: Q3V395 Mouse

SwissProt: Q569X8 Mouse

SwissProt: Q8BH74 Mouse

SwissProt: P52590 Rat

Unigene: 524574 Human

Unigene: 12568 Mouse

Unigene: 11398 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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