来一水AV@lysav|亚洲AV无码片VR一区二区三区 |国产亚洲精久久久久久无码|视色4se成人午夜精品久久

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
欧美激情一区二区三区在线|99精品视频在线观看免费
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-NuMA/Cy5 Conjugated antibody (bs-3512R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-3512R-Cy5
英文名稱1 Rabbit Anti-NuMA/Cy5 Conjugated antibody
中文名稱 Cy5標記的核有絲分裂器NuMA蛋白抗體
別    名 NUMA 1; NuMA protein; NUMA1; SP H antigen; Structural nuclear protein; Centrophilin stabilizes mitotic spindle in mitotic cells; Nuclear mitotic apparatus protein 1; Nuclear mitotic apparatus protein; NUMA1_HUMAN; NMP 22; NMP22; Nuclear matrix protein 22; Nuclear mitotic apparatus protein 1; Nuclear mitotic apparatus protein; NuMA protein; SP-H antigen.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  免疫學  染色質(zhì)和核信號  神經(jīng)生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 238kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NuMA
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
NuMA (Nuclear Mitotic Apparatus Protein) is an intranuclear protein and present in nucleus during interphase. At the onset of mitosis, it redistributes from the nucleus to two centrosomal structures that later will become part of the mitotic spindle pole. After anaphase, the protein redistributes from the spindle polar region into reforming nucleus. NuMA is an essential protein during mitosis for the terminal phases of chromosome separation and/or nuclear reassembly. Recently a study shows that NuMA is cleaved to a 180 to 200kDa during apoptosis.

Function:
Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions.

Subunit:
Homodimer. Also forms multiarm oligomers by association of C-terminal tail domains, oligomers may further assemble to form a hexagonal nuclear lattice-like network. Interacts with TNKS.

Subcellular Location:
Nucleus matrix. Chromosome. Cytoplasm, cytoskeleton, spindle pole. Note=Resides in the nuclear matrix during interphases. Dissociates from condensing chromosomes during early prophase, and relocates to the spindle poles via dynein/dynamin association, it remain there until the anaphase onset. Before the complete disintegration of the nuclear lamina. As mitosis progresses it reassociates with telophase chromosomes very early during nuclear reformation, before substantial accumulation of lamins on chromosomal surfaces is evident.
Isoform Numa-m: Cytoplasm. Note=Mainly clustered at the centrosomal region.
Isoform Numa-s: Cytoplasm. Note=Mainly clustered at the centrosomal region.

Post-translational modifications:
ADP-ribosylated by TNKS during mitosis.
Phosphorylated in the C-terminal tail during mitosis, probably by CDK1. Phosphorylation increases solubility and promotes association with dynein and subsequent translocation to the spindle poles.

Database links:

Entrez Gene: 4926 Human

Entrez Gene: 101706 Mouse

Entrez Gene: 308870 Rat

Omim: 164009 Human

SwissProt: Q14980 Human

SwissProt: Q3TH77 Mouse

SwissProt: Q4G051 Rat

Unigene: 325978 Human

Unigene: 66392 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

NuMA (Nuclear mitotic apparatus protein)是細胞核基質(zhì)中的一種高分子量蛋白質(zhì),具有一個特殊的細胞周期依賴性.核有絲分裂器蛋白NuMA與人類腫瘤細胞的惡性增殖相關(guān).
版權(quán)所有 2004-2026 www.73327.net 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
日韩精品一区在线观看麻豆| 人妻[21P]大胆| 天堂在\/线中文官网| 在线不卡的av杨幂| 91人人摸人人爽人人操| 国产国拍亚洲精品AV在线| 亚洲一区二区三区无码久久| 亚洲av无码一区二区三区在线观看| 国产爆乳无码一区二区麻豆| 国产精品亚洲一区二区无码| 亚洲AV无码乱码国产精品FC2 | 日韩视频一区二区三区在线观看| 人妻丰满熟妇AV无码区乱| 亚洲熟妇少妇任你躁在线观看无码| 亚洲人成人精品久久| 扒开粉嫩的小缝隙喷白浆| 一区二区三区欧美熟姨亚洲| 日韩乱码人妻无码中文字幕久久| 国产精品一区二区更多| 69久久无码一区人妻A片| 亚洲人成人无码网WWW国产| 无码八A片人妻少妇久久| 欧美变态口味重另类在线视频| 欧美乱妇狂野欧美在线视频| 大陆av片亚洲av片| 女浴室里赤裸裸洗澡丰满视频| 亚洲一区国产二区日本三区| 尤物色视频网站在线观看| 日韩人妻无码精品A片免费不卡| 年轻18GAY白嫩青少年| 久久久精品视频高清| 男女猛烈激情XX00免费视频| 国产白嫩护士被弄高潮| LULULU8 | 国产精品资源吧| 在线观看欧美黄片一区二区三区高清| 久久精品亚洲一区二区三区浴池| 欧美日韩亚洲精品系列| 无码粉嫩小泬无套在线观看A片| 亚洲国产一区二区三区综合片 | 天天干夜夜操狠狠插用力撞| 猫咪成人一二三区日韩国产|