来一水AV@lysav|亚洲AV无码片VR一区二区三区 |国产亚洲精久久久久久无码|视色4se成人午夜精品久久

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  人才招聘  關于我們  聯(lián)系我們
曰本无码人妻丰满熟妇啪啪|欧美三级在线播放|国产精品久久久久久久久久网
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Phospho-RCC1 (Ser11)/Cy5.5 Conjugated antibody (bs-3360R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3360R-Cy5.5
英文名稱1 Rabbit Anti-Phospho-RCC1 (Ser11)/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標記的磷酸化染色體濃縮調控蛋白1抗體
別    名 Cell cycle regulatory protein; CHC 1; CHC1; Chromosome condensation 1; Chromosome condensation protein 1; Guanine nucleotide releasing protein; HERC2; Ran GEF; RanGEF; RCC 1; RCC1 I; Regulator of chromosome condensation 1; Regulator of chromosome condensation; SHEP1; RCC1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 細胞生物  染色質和核信號  信號轉導  細胞凋亡  轉錄調節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human RCC1 around the phosphorylation site of Ser11
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Ran GTPase plays important roles in nucleocytoplasmic transport in interphase and in both spindle formation and nuclear envelope (NE) assembly during mitosis. The latter functions rely on the presence of high local concentrations of GTP bound Ran near mitotic chromatin. RanGTP localization has been proposed to result from the association of Ran's GDP/GTP exchange factor, RCC1, with chromatin , but Ran is shown here to bind directly to chromatin in two modes, either dependent or independent of RCC1, and, where bound, to increase the affinity of chromatin for NE membranes.

Function:
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

Subunit:
Interacts with ARRB2; the interaction is detected in the nucleus upon OR1D2 stimulation.

Subcellular Location:
Nucleus. Cytoplasm. Note=Becomes dispersed throughout the cytoplasm during mitosis.

Post-translational modifications:
N-terminal methylation by METTL11A/NTM1 is required for binding double-stranded DNA and stable chromatin association. Di-and trimethylation produce a permanent positive charge on the amino group, which facilitate electrostatic binding to the phosphate groups on DNA, while inhibiting histone-binding. Methylated tail helps retain RCC1 on chromosomes during nucleotide exchange on Ran.

Similarity:
Contains 7 RCC1 repeats.

Database links:

Entrez Gene: 1104 Human

Entrez Gene: 100088 Mouse

Entrez Gene: 682908 Rat

Omim: 179710 Human

SwissProt: P18754 Human

SwissProt: Q8VE37 Mouse

Unigene: 469723 Human

Unigene: 255045 Mouse

Unigene: 217123 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.73327.net 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
久久精品熟女亚洲AV麻豆| 色噜噜AV亚洲色一区二区| 少妇寂寞偷公乱400章深夜书屋| 女人18片毛片60分钟| 国产精品一区二区三区久久久久久久久 | 成人免费毛片AAAAAA片| 日本一级毛片高清免费观看| 日韩在线免费中文字幕| 午夜国产成人av在线播放| 欧美牲交a欧美牲交| 精品人妻大屁股白浆无码| 亚洲综合无码一区二区| 少妇荡乳情欲办公室456视频| 中文无遮挡H肉视频在线观看| 国产精品99久久久久久一区二区| 全免费A级毛片免费看| 午夜影院1000在线免费观看| 一本加勒比HEZYO无码A片| 四虎永久在线精品免费一区二区| 欧洲成在人线a免费视频 | 一区二区二区国产在线| 亚洲av首页在线观看| 日本丰满大乳人妻无码| 国产aⅴ激情无码久久久无码| 九九在线免费视频精品| 欧美一区二区三区在| 亚洲小说区图片区另类春色| 中文字幕一区二区三区不卡| 国产特级毛片AAAAAA| A级A片少妇高潮喷水片| 国产一区二区日韩欧美| 国产视频国产视频一二三区 | 日韩欧美人妻精品91高清久久| 伴郎粗大的内捧猛烈进出第一章| 亚洲AV午夜精品一区二区三区| 亚洲天堂av一区二区在线| 国产AV国片精品JK制服| 久久国产精品免费一区| 岛国片在线观看极品尤物| 久久毛片av| 特黄AAAAAAA片免费视频|