| 產(chǎn)品編號(hào) | bs-3628R-Gold |
| 英文名稱1 | Rabbit Anti-PRL3/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的磷酸酯酶3蛋白抗體 |
| 別 名 | PRL-R;Potentially prenylated protein tyrosine phosphatase; PRL 3; PRL R; PRLR: PRL3; PRLR; Protein tyrosine phosphatase 4a3; PTP 4A3: PTP4A3. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 腫瘤 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep, Guinea Pig, Danio) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 19kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PRL3/PTP4A3 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: PTP4A3 protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. It enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. It may be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. PTP4A3 interacts with tubulin. It belongs to the protein tyrosine phosphatase family. It is mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. It is consistently overexpressed in colon cancer metastasis. Subunit: Interacts with tubulin. Subcellular Location: Cell membrane. Early endosome. Tissue Specificity: Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis. Similarity: Belongs to the protein-tyrosine phosphatase family. Contains 1 tyrosine-protein phosphatase domain. Database links: Entrez Gene: 11156 Human Entrez Gene: 19245 Mouse Entrez Gene: 406460 Zebrafish Omim: 606449 Human SwissProt: O75365 Human SwissProt: Q9D658 Mouse SwissProt: Q6NX92 Zebrafish Unigene: 43666 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
