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Rabbit Anti-PRL3/FITC Conjugated antibody (bs-3628R-FITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3628R-FITC
英文名稱1 Rabbit Anti-PRL3/FITC Conjugated antibody
中文名稱 FITC標記的磷酸酯酶3蛋白抗體
別    名 PRL-R;Potentially prenylated protein tyrosine phosphatase; PRL 3; PRL R; PRLR: PRL3; PRLR; Protein tyrosine phosphatase 4a3; PTP 4A3: PTP4A3.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  信號轉導  轉錄調節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep, Guinea Pig, Danio)
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 19kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRL3/PTP4A3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
PTP4A3 protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. It enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. It may be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. PTP4A3 interacts with tubulin. It belongs to the protein tyrosine phosphatase family. It is mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. It is consistently overexpressed in colon cancer metastasis.

Subunit:
Interacts with tubulin.

Subcellular Location:
Cell membrane. Early endosome.

Tissue Specificity:
Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis.

Similarity:
Belongs to the protein-tyrosine phosphatase family.
Contains 1 tyrosine-protein phosphatase domain.

Database links:

Entrez Gene: 11156 Human

Entrez Gene: 19245 Mouse

Entrez Gene: 362930 Rat

Entrez Gene: 406460 Zebrafish

Omim: 606449 Human

SwissProt: O75365 Human

SwissProt: Q9D658 Mouse

SwissProt: Q78EG7 Rat

SwissProt: Q6NX92 Zebrafish

Unigene: 43666 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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