| 產(chǎn)品編號 |
bs-3675R-PE-Cy5 |
| 英文名稱1 |
Rabbit Anti-R-cadherin/PE-Cy5 Conjugated antibody
|
| 中文名稱 |
PE-Cy5標(biāo)記的R-鈣粘附分子抗體 |
| 別 名 |
Cadherin 4; Cadherin4; Cadherin-4 CDH4; R CAD; Retinal Cadherin. |
| 規(guī)格價格 |
100ul/2980元
購買 大包裝/詢價 |
| 說 明 書 |
100ul
|
| 研究領(lǐng)域 |
腫瘤 細(xì)胞生物 免疫學(xué) 激酶和磷酸酶 細(xì)胞粘附分子 糖蛋白 |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應(yīng) |
(predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, )
|
| 產(chǎn)品應(yīng)用 |
ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
81kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human R-cadherin(423-475aa) |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
Cadherins constitute a superfamily of calcium-dependent intercellular adhesion molecules and are thought to play a role in cell recognition and segregation, morphogenetic regulation, and tumor suppression. R Cadherin is expressed mainly in the brain but is also found in other tissues.
Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed mainly in brain but also found in other tissues.
Similarity:
Contains 5 cadherin domains.
Database links:
Entrez Gene: 1002 Human
Entrez Gene: 12561 Mouse
Entrez Gene: 114588 Rat
Omim: 603006 Human
SwissProt: P55283 Human
SwissProt: P39038 Mouse
SwissProt: Q80ZV4 Mouse
SwissProt: Q63149 Rat
Unigene: 473231 Human
Unigene: 598638 Human
Unigene: 184711 Mouse
Unigene: 382094 Mouse
Unigene: 392073 Mouse
Unigene: 214089 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
R-鈣粘附分子,是依賴鈣離子的細(xì)胞間糖蛋白粘附分子的一種，主要是參與細(xì)胞間同源性粘附、調(diào)控和介導(dǎo)細(xì)胞間相互反應(yīng)，在腫瘤的遷移、分化中起到一定的作用。在腦組織中表達(dá)外，其他組織中已有定位。
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