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Rabbit Anti-TNFSF9/CD137L/FITC Conjugated antibody (bs-3851R-FITC)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-3851R-FITC
英文名稱1 Rabbit Anti-TNFSF9/CD137L/FITC Conjugated antibody
中文名稱 FITC標記的腫瘤壞死因子配體超家族成員9抗體
別    名 4 1BB L; 4 1BB ligand; 4 1BBL; Cd137l; Cd157l; homolog of mouse 4 1BB L; homolog of mouse 4 1BBL; ILA ligand (TNF related); Ly63l; receptor 4 1BB ligand; Tumor necrosis factor (ligand) superfamily member 9; TNFL9_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  神經(jīng)生物學(xué)  細胞表面分子  t-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25-27kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNFSF9
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This cytokine belongs to the tumour necrosis factor (TNF) ligand family. It is a ligand for TNFRSF9, which is a costimulatory molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process, and in the generation of cytotoxic T cells. This cytokine is also shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is found to be expressed in various carcinoma cell lines, and is thought to be involved in T cell-tumour cell interaction.

Function:
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

Subunit:
Homotrimer.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Expressed in brain, placenta, lung, skeletal muscle and kidney.

Similarity:
Belongs to the tumor necrosis factor family.

Database links:

Entrez Gene: 8744 Human

Omim: 606182 Human

SwissProt: P41273 Human

Unigene: 1524 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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