来一水AV@lysav|亚洲AV无码片VR一区二区三区 |国产亚洲精久久久久久无码|视色4se成人午夜精品久久

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
亚洲成人高清一区二区|日本熟妇乱子伦A片|中文字幕日本人妻久久久免费
Rabbit Anti-phospho-PKA beta(Ser339)/BF647 Conjugated antibody (bs-4024R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-4024R-BF647
英文名稱1 Rabbit Anti-phospho-PKA beta(Ser339)/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的磷酸化蛋白激酶Aβ抗體
別    名 PRKACB (phospho Ser339); PRKACB (phospho S339); PRKACA (phospho Ser339); PRKACA (phospho S339); PKA alpha + beta (catalytic subunits) (phospho S339); PKA alpha + beta (phospho S339); PKA C beta; PKACB; PRKACB; Protein kinase cAMP dependent catalytic beta; cAMP-dependent protein kinase catalytic subunit beta; KAPCB_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human PKA beta around the phosphorylation site of Ser339
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Function:
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

Subunit:
A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. The cAMP-dependent protein kinase catalytic subunit binds PJA2 (By similarity).

Subcellular Location:
Cytoplasm. Cell membrane. Nucleus (By similarity). Note=Translocates into the nucleus (monomeric catalytic subunit) (By similarity). The inactive holoenzyme is found in the cytoplasm (By similarity).

Tissue Specificity:
Isoform 1 is most abundant in the brain, with low level expression in kidney. Isoform 2 is predominantly expressed in thymus, spleen and kidney. Isoform 3 and isoform 4 are only expressed in the brain.

Post-translational modifications:
Asn-3 is partially deaminated to Asp giving rise to 2 major isoelectric variants, called CB and CA respectively (By similarity).

Similarity:
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 282322 Cow

Entrez Gene: 282323 Cow

Entrez Gene: 5566 Human

Entrez Gene: 5567 Human

Entrez Gene: 18747 Mouse

Entrez Gene: 18749 Mouse

Entrez Gene: 25636 Rat

Omim: 176892 Human

Omim: 601639 Human

SwissProt: P00517 Cow

SwissProt: P17612 Human

SwissProt: P22694 Human

SwissProt: P05132 Mouse

SwissProt: P05206 Mouse

SwissProt: P27791 Rat

Unigene: 391 Cow

Unigene: 4420 Cow

Unigene: 487325 Human

Unigene: 631630 Human

Unigene: 16766 Mouse

Unigene: 19111 Mouse

Unigene: 103828 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.73327.net 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
精品人妻无码一区二区色欲产成人| 交换俱乐部娇妻奶呻吟啊视频| 大学生第一次破苞疼哭了| 精品丝袜久久久久久人妻懂色| 无码国产色欲XXXX视频| 国模杨依粉嫩蝴蝶150P| 欧美人与动性XXXXX杂性| 又大又紧又粗C欧美成人在线视频 欧美性受XXXX黑人XYX性爽 | 色哟哟在线观看国产精品| 国产男女猛烈无遮挡免费视频网站| 亚洲免费一区二区电影| 久久99国产精品久久99 | 国产亚洲色婷婷久久99精品| 亚洲AV无码一区二区二三区| 日本精品一区二区综合| 爱情岛论坛亚洲品质自拍网站| 国产成人亚洲综合网| 琪琪电影午夜理论片八戒八戒| 国产精品成人一区二区不卡| 国产偷v国产偷v亚洲高清| 高清亚洲中文字幕一区二区| 久久免费看少妇高潮V片特黄| 久久gvav| 国产色秀视频在线播放| 久久久欧美日韩精品| 黄桃AV无码免费一区二区三区| 亚洲 自拍 另类小说综合图区 | 亚洲欧美1区2区3区4区| 97人人模人人爽人人少妇| 国产SM主人调教女M视频| 亚洲熟妇AV一区二区三区| 免费观看亚洲人成网站| 中文字幕av无码一区二区蜜芽三区| 日韩殴美精品一区二区| 免费观看黃色A片观看| A片人人澡C片人人人妻| 国产乱一区二区三区夜夜爽| 2019精品国产品在线兔免费 | 曰批国产精品视频免费观看| 国产精品伦一区二区三级视频| 亚洲成人国产精品久久久|