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Rabbit Anti-Glycerol kinase/PE-Cy7 Conjugated antibody (bs-4062R-PE-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4062R-PE-Cy7
英文名稱1 Rabbit Anti-Glycerol kinase/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的甘油激酶抗體
別    名 ATP glycerol 3 phosphotransferase; GK; GK1; GKD; Glycerokinase; Glycerol kinase; Glycerol kinase deficiency; ATP:glycerol 3-phosphotransferase; GLPK_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Glycerol kinase
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Glycerol kinase catalyzes the formation of glycerol 3 phosphate from ATP and glycerol. Dihydroxyacetone and L glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway.

Function:
Key enzyme in the regulation of glycerol uptake and metabolism.

Subcellular Location:
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm.

Tissue Specificity:
Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.

DISEASE:
Defects in GK are the cause of GK deficiency (GKD) [MIM:307030]. This disease can be either symptomatic with episodic metabolic and CNS decompensation or asymptomatic with hyperglycerolemia and hyperglyceroluria only.

Similarity:
Belongs to the FGGY kinase family.

Database links:

Entrez Gene: 2710 Human

Entrez Gene: 14933 Mouse

Entrez Gene: 79223 Rat

Omim: 300474 Human

SwissProt: P32189 Human

SwissProt: Q64516 Mouse

SwissProt: Q63060 Rat

Unigene: 1466 Human

Unigene: 246682 Mouse

Unigene: 225941 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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