来一水AV@lysav|亚洲AV无码片VR一区二区三区 |国产亚洲精久久久久久无码|视色4se成人午夜精品久久

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
亚洲AV无码片VR一区二区三区|免费看美女被靠到爽的视频
Rabbit Anti-Livin/Biotin Conjugated antibody (bs-0738R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-0738R-Bio
英文名稱1 Rabbit Anti-Livin/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的凋亡抑制蛋白抗體
別    名 Baculoviral IAP repeat containing 7; Baculoviral IAP repeat containing protein 7; BIRC 7; BIRC7; BIRC7_HUMAN; KIAP; Kidney inhibitor of apoptosis protein; LIVIN; Livin inhibitor of apotosis; Melanoma inhibitor of apoptosis protein; ML IAP; MLIAP; RING finger protein 50; RNF 50; RNF50; Inhibitors of apoptosis proterins Livin.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  細(xì)胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Dog, Cow, )
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Livin C-terminus
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Livin is a novel member of the IAP protein family and contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin alpha and Livin beta. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. The two isoforms of Livin appear to have different functions and tissue distributions.

Function:
Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.

Subcellular Location:
Nucleus. Cytoplasm. Nuclear, and in a filamentous pattern throughout the cytoplasm.

Tissue Specificity:
Isoform 1 and isoform 2 are expressed at very low levels or not detectable in most adult tissues. Detected in adult heart, placenta, lung, lymph node, spleen and ovary, and in several carcinoma cell lines. Isoform 2 is detected in fetal kidney, heart and spleen, and at lower levels in adult brain, skeletal muscle and peripheral blood leukocytes.

Similarity:
Belongs to the IAP family.
Contains 1 BIR repeat.
Contains 1 RING-type zinc finger.

Database links:

Entrez Gene: 79444 Human

Omim: 605737 Human

SwissProt: Q96CA5 Human

Unigene: 256126 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Livin—屬于凋亡蛋白抑制因子家族(inhibitor of apoptosis proteins,IAP)
Livin是凋亡抑制蛋白家族的新成員,主要通過抑制Caspases蛋白發(fā)揮抑制細(xì)胞凋亡的作用,主要在胎盤組織中表達(dá),同時在一些腫瘤組織中呈高表達(dá),尤其是在黑色素瘤細(xì)胞系表達(dá)水平最高。
經(jīng)研究表明,Livin與腫瘤的發(fā)生、發(fā)展關(guān)系密切,是一個有潛在價值的腫瘤標(biāo)志物,此外,反義Livin以及Livin活性抑制物的研究有望成為腫瘤治療的新靶點。
版權(quán)所有 2004-2026 www.73327.net 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久久久99精品成人片| 午夜性色福利在线视频福利| 久久99精品久久久久久| 一本加勒比HEZYO中文无码| 三上悠亚SSⅠN939无码播放| 亚洲国产精华液网站w| 天天干,天天操,天天射| 久久av午夜一区二区三区| 国产精品久久久久久妇女主任| 亚洲欧美国产精品专区久久| 日本精品视频中文字幕| 小箩莉末发育娇小性色XXXX| 在线中文字幕亚洲日韩2020| 秋霞理论| 男男惩罚羞耻双腿分打屁股小作文| 日本精品资源在线观看| 亚洲成人无码一区二区| 久久久国产精华液| 日本免费播放一区二区视频 | 高清无码在线观看网站| 欧美一极黄片视频一区| 78午夜福利视频| 久久久久无码精品国产| 久久综合久久久久88| 欧美日韩国产一二三四区永久在线| 久久国产午夜精品免费一区二区 | 国产欧美一区二区精品忘忧草| 久久人人爽天天玩人人妻精品| 婷婷久草在线视频资源| 精品国产一区二区三区AV性色| 国产亚洲精品综合一区| 性做久久久久久久久| 精品国产日本一区二区| 亚洲熟妇av一区二区三区| 麻豆高清免费国产一区| 免费观看a级毛片| 亚婷婷洲AV久久蜜臀无码| 熟妇少妇任你躁在线无码| 日本熟妇一区二区三区在线视频| 熟妇人妻一区二区三区四区| 偷窥50个美女撒尿高清|