来一水AV@lysav|亚洲AV无码片VR一区二区三区 |国产亚洲精久久久久久无码|视色4se成人午夜精品久久

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
成人国产亚洲精品A区天堂蜜臀 |晚上看B站直播APP|色欧美片视频在线观看
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-CD71/Transferrin receptor/PE-Cy5 Conjugated antibody (bs-0988R-PE-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-0988R-PE-Cy5
英文名稱1 Rabbit Anti-CD71/Transferrin receptor/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標記的轉(zhuǎn)鐵蛋白受體抗體
別    名 CD 71; CD71; CD71 antigen; p90; T9; TFR 1; TFR; TFR1; TFRC; TR; Transferrin receptor (p90 CD71); Transferrin Receptor Protein 1; OTTHUMP00000208523; OTTHUMP00000208524; OTTHUMP00000208525; Transferrin receptor protein 1, serum form; TRFR.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  心血管  細胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  干細胞  轉(zhuǎn)錄調(diào)節(jié)因子  細胞表面分子  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Guinea Pig, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74/85kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Transferrin receptor
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Cellular uptake of iron occurs via receptor mediated endocytosis of ligand occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Useful in studies of dividing haematopoietic and tumour cell populations, and metabolic activity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C terminal binding site. The antigen is present on most dividing cells, including normally cycling in vivo hematopoietic progenitor cells, mitogenically stimulated cells in vitro, some primary tumor cells and most proliferating cells in vitro.

Function:
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

Subunit:
Homodimer; disulfide-linked. Binds one transferrin molecule per subunit. Interacts with SH3BP4.

Subcellular Location:
Secreted and Cell membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Post-translational modifications:
N- and O-glycosylated, phosphorylated and palmitoylated. The serum form is only glycosylated. Proteolytically cleaved on Arg-100 to produce the soluble serum form (sTfR). Palmitoylated on both Cys-62 and Cys-67. Cys-62 seems to be the major site of palmitoylation.

Similarity:
Belongs to the peptidase M28 family. M28B subfamily.
Contains 1 PA (protease associated) domain.

Database links:

Entrez Gene: 7037 Human

Entrez Gene: 22042 Mouse

Entrez Gene: 64678 Rat

Omim: 190010 Human

SwissProt: P02786 Human

SwissProt: Q62351 Mouse

SwissProt: Q99376 Rat

Unigene: 529618 Human

Unigene: 28683 Mouse

Unigene: 98672 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

轉(zhuǎn)鐵蛋白及轉(zhuǎn)鐵蛋白受體(TfnrR)是機體鐵代謝中的重要因子,鐵是細胞生長增殖、代謝的必需元素,轉(zhuǎn)鐵蛋白受體(TfR)介導(dǎo)的胞吞作用是細胞攝取鐵的主要途徑。腫瘤細胞因增殖生長旺盛,對鐵的需求高,所以腫瘤細胞有比正常細胞更多的轉(zhuǎn)鐵蛋白受體的表達。
版權(quán)所有 2004-2026 www.73327.net 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
亚洲欧美国产精品无码中文字| 无码国产精品一区二区免费16| 国产妇女馒头高清泬20P多| av观看| 女主播喷水免费直播| 国产熟女肥臀精品国产馆乱| 免费三级网站| 粗大的内捧猛烈进出小视频| 男男开小嫩苞好深啊H窑子开| 日本一区二区三区夜视频| 国产99久久久久久免费看| 欧美日韩在线视频| 非洲老熟妇一区二区三区久久久| 英语老师解开裙子坐我腿中间| 亚洲无AV在线中文字幕| 香蕉久久久久久AV成人 | 久久亚洲av午夜福利精品二区| 亚洲午夜精品一区在线| 中文字幕色AV一区二区三区| 国产精品成人一区二区三区 | 护士的初苞被强开了| 国产丰满老熟女重口对白| 天天爽夜夜爽人人爽,qc| AAA级久久久精品无码片| 欧美日韩精品久久免费看| 我的变态室友(H)三攻一受| 久久国产精品波多野结衣AV| 久久erav| 久久久精品一区AAA片| 午夜精品久久久久久| 麻豆国产精品色欲AV亚洲三区| 国产精品久久久久久69堂| 成人欧美一区二区三区黑人 | 久久精品色妇熟妇丰满人妻5O| 免费大黄网站在线观| 久久乐亚洲国产精品综合| 久久久久久久久久久久久久一区二区| 国产男女无遮挡猛进猛出| 国产69精品久久久久999小说| 中文字幕亚洲无线码在线一区| 无码人妻AV一二区二区三区|