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Rabbit Anti-AKIRIN2/Gold Conjugated antibody (bs-9082R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-9082R-Gold
英文名稱1 Rabbit Anti-AKIRIN2/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的AKIRIN2蛋白抗體
別    名 AKIR2_HUMAN; AKIRIN 2; Akirin-2; Akirin2; C6orf166; dJ486L4.2; FBI1; FLJ10342; Fourteen three three beta interactant 1.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AKIRIN2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.

Function:
Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).

Subunit:
Interacts with YWHAB (By similarity).

Subcellular Location:
Nucleus

Tissue Specificity:
Widely expressed with the highest expression in peripheral blood leukocytes

Similarity:
Belongs to the akirin family.

Database links:

Entrez Gene: 55122 Human

Entrez Gene: 433693 Mouse

Entrez Gene: 297968 Rat

Omim: 615165 Human

SwissProt: Q53H80 Human

SwissProt: B1AXD8 Mouse

SwissProt: Q25C79 Rat

Unigene: 485915 Human

Unigene: 389532 Mouse

Unigene: 399624 Mouse

Unigene: 3858 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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