| 產(chǎn)品編號(hào) | bs-0739R-BF488 |
| 英文名稱1 | Rabbit Anti-PAP2c/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的磷脂酸磷酸酶2C抗體 |
| 別 名 | PPAP2C; EC 3.1.3.4; Phosphatidic acid phosphatase 2c; Lipid phosphate phosphohydrolase 2; LPP2; PAP 2c; PAP2 G; PAP2 gamma; Phosphatidic acid phosphatase 2c; Phosphatidic acid phosphatase type 2C; Phosphatidate phosphohydrolase type 2c; Type 2 phosphatidic acid phosphatase gamma; PAP2c; PAP-2c; PAP2G; PAP2-gamma; LPP2_HUMAN; PAP2-G. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 脂蛋白 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 33kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PAP2c |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]. Function: Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is PA > C-1-P > LPA > S-1-P. Subunit: Homodimer. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Found mainly in brain, pancreas and placenta. Similarity: Belongs to the PA-phosphatase related phosphoesterase family. Database links: Entrez Gene: 8612 Human Omim: 607126 Human SwissProt: O43688 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PAP2c-磷脂酸磷酸酶-2C 又稱：PAP2-gamma、PAP2-G主要用于胰島素、糖及脂肪代謝方面的研究。 |
