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Rabbit Anti-PAX1/PE Conjugated antibody (bs-1199R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
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技術(shù)支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1199R-PE
英文名稱1 Rabbit Anti-PAX1/PE Conjugated antibody
中文名稱 PE標記的配對盒基因1抗體
別    名 HUP48; OTTHUMP00000030407; Paired box 1; Paired box gene 1; Paired box protein Pax 1; Paired domain gene HuP48; PAX 1; PAX1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  發(fā)育生物學(xué)  信號轉(zhuǎn)導(dǎo)  干細胞  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PAX1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations. [provided by RefSeq, Mar 2012]

Function:
This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 paired domain.

Database links:

Entrez Gene: 5075 Human

Entrez Gene: 18503 Mouse

Entrez Gene: 311505 Rat

Omim: 167411 Human

SwissProt: P15863 Human

SwissProt: P09084 Mouse

Unigene: 349082 Human

Unigene: 315502 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

同源結(jié)構(gòu)域蛋白(Homeodomain Proteins)
PAX蛋白在器官發(fā)生中起關(guān)鍵作用,包括促進細胞增殖、細胞世系的特異化、遷移和存活。一些PAX基因在多種癌癥類型中表達,因此可以作為有用的腫瘤標志物。
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