| 產(chǎn)品編號(hào) | bs-0420R-BF488 |
| 英文名稱1 | Rabbit Anti-PIBF/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的孕激素誘導(dǎo)阻斷因子抗體 |
| 別 名 | progesterone induced blocking factor; KIAA1008; PIBF 1; PIBF; PIBF1; Progesterone immunomodulatory binding factor 1; Progesterone induced blocking factor 1; PIBF1_HUMAN; RP11 505F3.1; CEP90; C13orf24; RP11-505F3.1. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 免疫學(xué) 細(xì)胞周期蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, Rat, (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 83kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PIBF |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: C13orf24 is also known as Progesterone-induced-blocking factor 1 (PIBF1). PIBF1 is synthesized by lymphocytes of healthy pregnant women in the presence of progesterone and inhibits arachidonic acid release, by acting on the phospholipase A2 enzyme, inducing a Th2 biased immune response. It also controls NK activity, and modifies the cytokine balance exerting an anti-abortive effect. Function: Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect. Tissue Specificity: Expressed at highest levels in testis. Moderate expression is detected in spleen, thymus, prostate, ovary, small intestine, and colon. Database links: Entrez Gene: 10464 Human Entrez Gene: 52023 Mouse Omim: 607532 Human SwissProt: Q8WXW3 Human Unigene: 441926 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 孕激素誘導(dǎo)阻斷因子又稱孕酮誘導(dǎo)的封閉因子性蛋白。 妊娠期間淋巴細(xì)胞生成孕酮受體且釋放一種稱之為孕酮誘導(dǎo)的封閉因子性蛋白(PIBF),PIBF有很強(qiáng)的抗NK細(xì)胞活性,PIBF陽(yáng)性淋巴細(xì)胞分泌IL-10。 |
