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Rabbit Anti-FIGNL1/RBITC Conjugated antibody (bs-9433R-RBITC)
訂購(gòu)熱線:400-901-9800
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說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-9433R-RBITC
英文名稱1 Rabbit Anti-FIGNL1/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的FIGNL1蛋白抗體
別    名 Fidgetin like protein 1; fidgetin-like 1; FIGL1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  細(xì)胞分化  細(xì)胞骨架  細(xì)胞外基質(zhì)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FIGNL1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
FIGNL1 is a 674 amino acid protein belonging to the AAA ATPase family. FIGNL1 exists as a hexamer that undergoes alternative splicing to produce two isoforms. FIGNL1 utilizes magnesium as a cofactor and is phosphorylated upon DNA damage, probably by ATM or ATR. FIGNL1 is suggested to regulate osteoblast proliferation and differentiation. FIGNL1 is encoded by a gene located on human chromosome 7, which consists about 158 milllion bases, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

Function:
May regulate osteoblast proliferation and differentiation (By similarity).

Subunit:
Hexamer (By similarity).

Similarity:
Belongs to the AAA ATPase family.

Database links:

Entrez Gene: 63979 Human

Entrez Gene: 63979 Mouse

SwissProt: Q6PIW4 Human

SwissProt: Q8BPY9 Mouse

Unigene: 137516 Human

Unigene: 236114 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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