| 產(chǎn)品編號 |
bs-5199R-Cy7 |
| 英文名稱1 |
Rabbit Anti-phospho-ATG9A(Ser735)/Cy7 Conjugated antibody
|
| 中文名稱 |
Cy7標記的磷酸化自噬相關(guān)蛋白9A抗體 |
| 別 名 |
APG9 autophagy 9-like 1; APG9 like 1; APG9-like 1; APG9L1; ATG9; ATG9 autophagy related 9 homolog A; ATG9 autophagy related 9 homolog A (S. cerevisiae); ATG9A; ATG9A_HUMAN; Autophagy 9-like 1 protein; Autophagy related protein 9A; Autophagy-related protein 9A; mATG9; MGD3208; OTTHUMP00000206046; OTTHUMP00000206048; OTTHUMP00000206049; OTTHUMP00000206062. |
| 規(guī)格價格 |
100ul/2980元
購買 大包裝/詢價 |
| 說 明 書 |
100ul
|
| 產(chǎn)品類型 |
磷酸化抗體 |
| 研究領(lǐng)域 |
腫瘤 心血管 細胞生物 免疫學 神經(jīng)生物學 信號轉(zhuǎn)導 細胞凋亡 線粒體 泛素 |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應(yīng) |
(predicted: Human, Mouse, Rat, Pig, Cow, )
|
| 產(chǎn)品應(yīng)用 |
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
94kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated Synthesised phosphopeptide derived from human ATG9A around the phosphorylation site of Ser735 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
Plays a role in autophagy. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and FAM48A.
Function:
Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.
Subunit:
Interacts with SUPT20H.
Subcellular Location:
Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation-induced redistribution depends on ULK1, ATG13, as well as SH3GLB1.
Similarity:
Belongs to the ATG9 family.
Database links:
Entrez Gene: 79065 Human
Entrez Gene: 245860 Mouse
Entrez Gene: 363254 Rat
Omim: 612204 Human
SwissProt: Q7Z3C6 Human
SwissProt: Q68FE2 Mouse
SwissProt: Q5FWU3 Rat
Unigene: 323363 Human
Unigene: 479951 Mouse
Unigene: 35248 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|
|
