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Rabbit Anti-SRP68/APC Conjugated antibody (bs-2381R-APC)
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訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-2381R-APC
英文名稱1 Rabbit Anti-SRP68/APC Conjugated antibody
中文名稱 APC標(biāo)記的信號識別顆粒抗體
別    名 Signal recognition particle 68 kDa; Signal recognition particle subunit SRP68; Signal recognition particle 68 kDa protein; SRP 68; Srp68; SRP68_HUMAN.   
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 免疫學(xué)  染色質(zhì)和核信號  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SRP68
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.

Function:
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.

Subunit:
Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

Subcellular Location:
Cytoplasm. Nucleus, nucleolus.

Similarity:
Belongs to the SRP68 family.

Database links:

Entrez Gene: 6730 Human

Entrez Gene: 217337 Mouse

Entrez Gene: 363707 Rat

Omim: 604858 Human

SwissProt: Q9UHB9 Human

SwissProt: Q8BMA6 Mouse

Unigene: 514495 Human

Unigene: 29655 Mouse

Unigene: 68 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

信號識別顆粒(Signalrecognitionparticle,SRP)是介導(dǎo)蛋白識別轉(zhuǎn)運(yùn)其中普遍存在的機(jī)制之一,細(xì)胞內(nèi)蛋白質(zhì)的定向轉(zhuǎn)移是蛋白質(zhì)質(zhì)量數(shù)量控制體系的一個(gè)重要環(huán)節(jié),SRP對參與這一過程的功能基因和蛋白,尤其是蛋白的靶向輸送機(jī)制的研究對揭示細(xì)胞的分化、代謝和病變具有重大的理論意義.
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