產(chǎn)品編號 |
bs-5438R-PE-Cy5 |
英文名稱1 |
Rabbit Anti-phospho-MAP4(Ser941)/PE-Cy5 Conjugated antibody
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中文名稱 |
PE-Cy5標(biāo)記的磷酸化微管相關(guān)蛋白4抗體 |
別 名 |
MAP4 (phospho S941); p-MAP4 (phospho S941); MAP4(phospho S941); DKFZp779A1753; MAP-4; MAP4; MAP4_HUMAN; MGC8617; Microtubule associated protein 4; Microtubule-associated protein 4; OTTHUMP00000210723; OTTHUMP00000210725; OTTHUMP00000210727; OTTHUMP00000210730. |
規(guī)格價(jià)格 |
100ul/2980元
購買 大包裝/詢價(jià) |
說 明 書 |
100ul
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產(chǎn)品類型 |
磷酸化抗體 |
研究領(lǐng)域 |
細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 細(xì)胞骨架 |
抗體來源 |
Rabbit |
克隆類型 |
Polyclonal |
交叉反應(yīng) |
(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
|
產(chǎn)品應(yīng)用 |
IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
分 子 量 |
121kDa |
性 狀 |
Lyophilized or Liquid |
濃 度 |
1mg/ml |
免 疫 原 |
KLH conjugated Synthesised phosphopeptide derived from human MAP4 around the phosphorylation site of Ser941 |
亞 型 |
IgG |
純化方法 |
affinity purified by Protein A |
儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The MAP4 (Microtubule associated protein 4)is a non neuronal microtubule associated protein. It promotes microtubule assembly.The phosphorylation of the Pro rich region in the C-terminus negatively regulates MAP4 activity to promote microtubule assembly.
Function: Non-neuronal microtubule-associated protein. Promotes microtubule assembly.
Subunit: Interacts with SEPT2; this interaction impedes tubulin-binding.
Subcellular Location: Cytoplasm, cytoskeleton.
Post-translational modifications: Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Phosphorylation on Ser-787 negatively regulates MAP4 activity to promote microtubule assembly. Isoform 3 is phosphorylated on Ser-337 and Ser-338.
Similarity: Contains 4 Tau/MAP repeats.
Database links: UniProtKB/Swiss-Prot: P27816.3
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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