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Rabbit Anti-Cyclin A1/BF594 Conjugated antibody (bs-5739R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
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技術支持:techsupport@73327.net
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-5739R-BF594
英文名稱1 Rabbit Anti-Cyclin A1/BF594 Conjugated antibody
中文名稱 BF594標記的周期素A1蛋白抗體
別    名 CCN A1; Cyclin-A1; CCNA 1; CCNA1; CyclinA1; MGC132235; MGC159139.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cyclin A1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Cyclin A1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin A1 is expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. It binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. Cyclin A1 was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins.

Function:
Essential for the control of the cell cycle at the G1/S (start) and the G2/M (mitosis) transitions.

Subcellular Location:
Nucleus. Cytoplasm. Cytoplasmic when associated with SCAPER.

Similarity:
Belongs to the cyclin family. Cyclin AB subfamily.

Database links:

Entrez Gene: 8900 Human

Entrez Gene: 12427 Mouse

Omim: 604036 Human

SwissProt: P78396 Human

SwissProt: Q61456 Mouse

Unigene: 417050 Human

Unigene: 4815 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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