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Rabbit Anti-MOCOS/Gold Conjugated antibody (bs-5936R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-5936R-Gold
英文名稱1 Rabbit Anti-MOCOS/Gold Conjugated antibody
中文名稱 膠體金標記的原癌基因絲氨酸/蘇氨酸蛋白激酶MOS抗體
別    名 c mos; c-mos; MSV; y Oocyte maturation factor mos; Proto oncogene serine / threonine protein kinase mos; FLJ20733; HMCS; MCS; MoCo sulfurase; Molybdenum cofactor sulfurase; MOS; v mos Moloney murine sarcoma viral oncogene homolog; MOCOS_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  發(fā)育生物學(xué)  染色質(zhì)和核信號  干細胞  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Horse, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MOCOS
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
MOCOS sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH; MIM 607633) and aldehyde oxidase (AOX1; MIM 602841), which is required for their enzymatic activities (Ichida et al., 2001 [PubMed 11302742]).[supplied by OMIM, Feb 2010]

Function:
Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

DISEASE:
Defects in MOCOS are the cause of xanthinuria type 2 (XU2) [MIM:603592]. Xanthinuria is characterized by excretion of very large amounts of xanthine in the urine and a tendency to form xanthine stones. Uric acid is strikingly diminished in serum and urine. In addition, patient suffering of XU2 cannot metabolize allopurinol into oxypurinol due to dual deficiency of xanthine dehydrogenase and aldehyde oxidase.

Similarity:
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
MOCOS subfamily.
Contains 1 MOSC domain.

Database links:

Entrez Gene: 55034 Human

Omim: 613274 Human

SwissProt: Q96EN8 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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