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Rabbit Anti-Myotrophin/Biotin Conjugated antibody (bs-11891R-Bio)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11891R-Bio
英文名稱1 Rabbit Anti-Myotrophin/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的顆粒細(xì)胞分化蛋白抗體
別    名 FLJ31098; FLJ99857; GCDP; Granule cell differentiation protein; MTPN; MTPN_HUMAN; Myotrophin; Protein V 1; Protein V-1; V 1; MTPN_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 心血管  細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 13kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from humam Myotrophin/GCDP
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008]

Function:
Potential role in cerebellar morphogenesis. May function in differentiation of cerebellar neurons, particularly of granule cells. Seems to be associated with cardiac hypertrophy.

Subunit:
Interacts with RELA (By similarity). Interacts with the heterodimer formed by CAPZA1 and CAPZB.

Subcellular Location:
Cytoplasm (Probable). Nucleus (By similarity). Cytoplasm, perinuclear region (By similarity).

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the myotrophin family.
Contains 3 ANK repeats.

Database links:

Entrez Gene: 136319 Human

Entrez Gene: 14489 Mouse

Entrez Gene: 79215 Rat

Entrez Gene: 403487 Dog

Omim: 606484 Human

SwissProt: Q863Z4 Dog

SwissProt: P58546 Human

SwissProt: P62774 Mouse

SwissProt: P62775 Rat

SwissProt: Q7T2B9 Zebrafish

Unigene: 602015 Human

Unigene: 182746 Mouse

Unigene: 3239 Rat

Unigene: 75187 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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