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Rabbit Anti-Plexin A4/Gold Conjugated antibody (bs-11936R-Gold)
訂購(gòu)熱線:400-901-9800
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說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11936R-Gold
英文名稱(chēng)1 Rabbit Anti-Plexin A4/Gold Conjugated antibody
中文名稱(chēng) 膠體金標(biāo)記的神經(jīng)叢蛋白A4抗體
別    名 FAYV2820; KIAA1550; PLEXA4; Plexin-A4; PlexinA4; PLXA4_HUMAN; PLXNA4; PLXNA4A; PLXNA4B; PRO34003; UNQ2820/PRO34003.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 發(fā)育生物學(xué)  神經(jīng)生物學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 210kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Plexin A4
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Forms a receptor complex with neuropilin-1 and can propagate semaphorin-3A elicited inhibitory signals into cells and neurons.

Function:
Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm

Subunit:
Interacts with NRP1 and NRP2

Subcellular Location:
Cell membrane; Single-pass type I membrane protein

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the plexin family.
Contains 4 IPT/TIG domains.
Contains 3 PSI domains.
Contains 1 Sema domain.

Database links:

Entrez Gene: 91584 Human

Entrez Gene: 243743 Mouse

Entrez Gene: 312213 Rat

Omim: 604280 Human

SwissProt: Q9HCM2 Human

SwissProt: Q80UG2 Mouse

Unigene: 511454 Human

Unigene: 444029 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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