| 產(chǎn)品編號(hào) | bs-12109R-BF488 |
| 英文名稱1 | Rabbit Anti-P2X5b/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的三磷酸腺苷受體P2X5b抗體 |
| 別 名 | ATP receptor; ATP receptor subunit; ionotropic ATP receptor P2X5; MGC47755; P2RX5; P2X purinoceptor 5; P2X5; P2X5R; Purinergic receptor; Purinergic receptor P2X ligand gated ion channel 5; P2RX5_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 細(xì)胞凋亡 通道蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 47kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human P2X5b |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP. Function: P2X5b belongs to the family of purinoceptors for ATP. This receptor functions as a ligand gated ion channel. Several characteristic motifs of ATP gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Three transcript variants encoding distinct isoforms have been identified for this gene. Subunit: Functional P2XRs are organized as homomeric and heteromeric trimers Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed at high levels in brain and immune system. Similarity: Belongs to the P2X receptor family. Database links: Entrez Gene: 5026 Human Omim: 602836 Human SwissProt: Q8IXW4 Human SwissProt: Q93086 Human Unigene: 408615 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
