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Rabbit Anti-DNER/BF488 Conjugated antibody (bs-12115R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12115R-BF488
英文名稱1 Rabbit Anti-DNER/BF488 Conjugated antibody
中文名稱 BF488標記的腦表皮生長因子跨膜蛋白DNER抗體
別    名 Brain EGF repeat-containing transmembrane protein; Bret; Delta and Notch-like epidermal growth factor-related receptor; Delta/notch-like EGF-related receptor; Dner; DNER_HUMAN; PRO299; Transmembrane protein Bet; UNQ26.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  干細胞  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 75kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DNER
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Function:
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Subunit:
Interacts with AP1G1. Interacts with NOTCH1.

Subcellular Location:
Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.

Tissue Specificity:
Expressed in brain, spinal cord and adrenal gland.

Similarity:
Contains 10 EGF-like domains.
Contains 1 follistatin-like domain.

Database links:

Entrez Gene: 92737 Human

Entrez Gene: 227325 Mouse

Entrez Gene: 316573 Rat

Omim: 607299 Human

SwissProt: Q8NFT8 Human

SwissProt: Q8JZM4 Mouse

Unigene: 234074 Human

Unigene: 292560 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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