| 產(chǎn)品編號 |
bs-14053R-PE-Cy3 |
| 英文名稱1 |
Rabbit Anti-CREB5/PE-Cy3 Conjugated antibody
|
| 中文名稱 |
PE-Cy3標記的環(huán)腺苷酸應答元件結(jié)合蛋白5抗體 |
| 別 名 |
cAMP response element binding protein 5; cAMP response element binding protein CRE Bpa; cAMP response element-binding protein CREBPa; cAMP responsive element binding protein 5; cAMP responsive element binding protein 5 isoform alpha; cAMP-responsive element-binding protein 5; CRE BPA; CRE-BPa; CREB 5; CREB-5; CREB5; CREB5_HUMAN; CREBPA; cyclic AMP responsive element binding protein 5; Cyclic AMP-responsive element-binding protein 5. |
| 規(guī)格價格 |
100ul/2980元
購買 大包裝/詢價 |
| 說 明 書 |
100ul
|
| 研究領(lǐng)域 |
細胞生物 染色質(zhì)和核信號 信號轉(zhuǎn)導 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學 |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應 |
Mouse,
(predicted: Human, Rat, Chicken, Dog, Cow, Horse, )
|
| 產(chǎn)品應用 |
ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
57kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human CREB5 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Function:
Binds to the cAMP response element and activates transcription.
Subunit:
Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the bZIP family.
Contains 1 bZIP domain.
Contains 1 C2H2-type zinc finger.
Database links:
Entrez Gene: 9586 Human
Entrez Gene: 231991 Mouse
Entrez Gene: 500131 Rat
SwissProt: Q02930 Human
SwissProt: Q8K1L0 Mouse
Unigene: 437075 Human
Unigene: 321138 Mouse
Unigene: 210235 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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