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Rabbit Anti-Sohlh1/BF647 Conjugated antibody (bs-12278R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12278R-BF647
英文名稱1 Rabbit Anti-Sohlh1/BF647 Conjugated antibody
中文名稱 BF647標記的精子卵子結合生成堿性螺旋蛋白抗體
別    名 GM110; Helix Loop Helix Protein TOHLH1; Sohlh1; SOLH1_HUMAN; Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1; TOHLH1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  發(fā)育生物學  干細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Sohlh1 (51-118aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
SOHLH1 is a 328 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one bHLH domain through which it may function as a transcription factor during oogenesis and spermatogenesis. The gene encoding SOHLH1 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.

Function:
Probable transcription factor required during spermatogenesis and oogenesis.

Subcellular Location:
Cytoplasm. Nucleus.

DISEASE:
Note=Genetic variations in SOHLH1 may be associated with non-obstructive azoospermia.

Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.

Database links:
UniProtKB/Swiss-Prot: Q5JUK2.4

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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