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Rabbit Anti-HOXB6/Gold Conjugated antibody (bs-12194R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12194R-Gold
英文名稱1 Rabbit Anti-HOXB6/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的同源盒蛋白B6抗體
別    名 HGNC:5117; homeo box B6; Homeobox protein Hox B6; Hox-2.2; HOX2; HOX2B; HU-2; HXB6_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細(xì)胞生物  發(fā)育生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from huuman HOXB6 (101-200aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
HoxB6 is cytoplasmically expressed throughout fetal epidermal development, but displays nuclear expression in normal adult skin. HoxB6 protein also has nuclear expression in hyperproliferative skin conditions, but appears to be localized in the cytoplasm in basal and squamous cell carcinomas. HoxB6 genes are also expressed in normal adult lung.

Function:
HOXB6 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms.

Subcellular Location:
Nuclear

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the Antp homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 3216 Human

Entrez Gene: 15414 Mouse

Entrez Gene: 497986 Rat

Omim: 142961 Human

SwissProt: P17509 Human

SwissProt: P09023 Mouse

Unigene: 98428 Human

Unigene: 215 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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