| 產(chǎn)品編號 | bs-16861R-BF488 |
| 英文名稱1 | Rabbit Anti-KTEL1/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的骨髓增生異常綜合征相關(guān)蛋白抗體 |
| 別 名 | C3orf9; CAP10 like 46 kDa protein; CAP10 like protein, 46 kDa; CLP46; hCLP46; KDELC family like 1; KDELCL1; KTEL (Lys Tyr Glu Leu) containing 1; KTEL motif containing protein 1; KTELC1; MDS010; MDSRP; myelodysplastic syndromes relative protein; POGLUT1; protein O glucosyltransferase 1; Rumi; x 010 protein. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 43kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KTEL1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: CLP46 is a KTEL motif-containing protein that belongs to the CAP10 family. The KTEL motif at the C-terminus of CLP46 is an endoplasmic reticulum (ER) retention signal which localizes the CLP46 protein to the lumen of the ER. CLP46 is thought to promote cell proliferation and is also believed to be involved with hepatic functions. The Drosophila protein rumi, a CAP10 protein and likely similar in function to CLP46, uses glucosylation to act as a Notch signaling regulator. Expressed in varying degrees in most adult tissue, CLP46 is especially abundant in the liver. CLP46 is not expressed in detectable levels in colon, thymus or small intestine. Human CLP46 shares 94% and 91% sequence similarity with its bovine and mouse homologs, respectively. Function: UDP-glucosyltransferase. Subcellular Location: Endoplasmic reticulum lumen. Tissue Specificity: Expressed in most adult tissues at different intensities. Abundantly expressed in liver. Expressed also in brain, heart, skeletal muscle, spleen, kidney, placenta, lung and peripheral blood leukocyte. Not detectable in colon, thymus and small intestine. Similarity: Belongs to the glycosyltransferase 90 family. Database links: Entrez Gene: 56983 Human Entrez Gene: 224143 Mouse SwissProt: Q8NBL1 Human SwissProt: Q8BYB9 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
