產(chǎn)品編號 | bs-17387R-PE-Cy7 |
英文名稱1 | Rabbit Anti-HRC/PE-Cy7 Conjugated antibody |
中文名稱 | PE-Cy7標(biāo)記的HRC蛋白抗體 |
別 名 | HCP; HRC; HRC histidine rich calcium binding protein; MGC133236; Sarcoplasmic reticulum histidine-rich calcium-binding protein; SRCH_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 結(jié)合蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 77kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HRC |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: HRC is a 699 amino acid that binds low-density lipoprotein with high affinity. As a high capacity calcium binding protein, HRC regulates the sequestration and release of calcium in the lumen of the junctional sarcoplasmic reticulum (SR) of cardiac, skeletal and smooth muscle. This mechanism may involve direct interaction between HRC and the cytoplasmic domain of Triadin, an integral membrane protein of the SR. The gene encoding HRC maps to human chromosome 19q13.33 and mouse chromosome 7 B4 Function: May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle. Subcellular Location: Sarcoplasmic reticulum lumen. Similarity: To rabbit HRC. Database links: Entrez Gene: 3270 Human Omim: 142705 Human SwissProt: P23327 Human Unigene: 436885 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |