| 產(chǎn)品編號 | bs-17512R-BF488 |
| 英文名稱1 | Rabbit Anti-Skuld/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的Skuld蛋白抗體 |
| 別 名 | CG9936-PC isoform C; Cg9936-pd isoform d; Jlkjlkj; MED13_DROME; Med13; Mediator complex subunit 13; Pap/DTRAP240; Protein blind spot; skd; Transcriptional coactivator blind spot; Trap240. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 發(fā)育生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 280kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Fruit fly Skuld |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Sklud is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Required for leg and eye development and macrochaete specification or differentiation. Negatively regulates sex comb development. Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for leg and eye development and macrochaete specification or differentiation. Negatively regulates sex comb development. Required for activated transcription of the MtnB and MtnD genes. Subunit: Component of the Cdk8 module of the Mediator complex, composed of CycC, Cdk8, kto and skd. Subcellular Location: Nuclear Similarity: Belongs to the Mediator complex subunit 13 family. Database links: Entrez Gene: 43906 Fruit fly (Drosophila melanogaster) SwissProt: Q7KTX8 Fruit fly (Drosophila melanogaster) Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
