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Rabbit Anti-TNPO3/PE-Cy7 Conjugated antibody (bs-18158R-PE-Cy7)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@73327.net
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@73327.net
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-18158R-PE-Cy7
英文名稱1 Rabbit Anti-TNPO3/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的轉(zhuǎn)運(yùn)蛋白3抗體
別    名 TNPO 3; Imp12; Importin 12; Importin-12; IPO12; MTR10A; TNPO 3; TNPO3; TNPO3_HUMAN; Transportin 3; Transportin SR; Transportin-3; Transportin-SR; TRN SR; TRN-SR; TRN-SR2; TRNSR.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  脂蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 104kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNPO3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010]

Function:
Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins SFRS1 and SFRS2, by recognizing phosphorylated RS domains.

Subunit:
Interacts with phosphorylated SFRS1 and SFRS2. Interacts with NUP62 and RBM4.

Subcellular Location:
Cytoplasm. Nucleus.

Database links:

Entrez Gene: 23534 Human

Entrez Gene: 320938 Mouse

Omim: 610032 Human

SwissProt: Q9Y5L0 Human

SwissProt: Q6P2B1 Mouse

Unigene: 193613 Human

Unigene: 276381 Mouse

Unigene: 304472 Mouse

Unigene: 352219 Mouse

Unigene: 424508 Mouse

Unigene: 429470 Mouse

Unigene: 439108 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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