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Rabbit Anti-TRIP/Biotin Conjugated antibody (bs-4983R-Bio)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-4983R-Bio
英文名稱1 Rabbit Anti-TRIP/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的腫瘤壞死因子受體相互作用蛋白抗體
別    名 RING finger protein 206; RNF206; TRAF Interacting Protein; TRAIP; TRIP.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.

Function:
Inhibits activation of NF-kappa-B mediated by TNF.

Subunit:
Binds TRAF1 and TRAF2 and is part of the receptor-TRAF signaling complex. Interacts with CYLD.

Subcellular Location:
Cytoplasm. Cytoplasm, perinuclear region.

Similarity:
Contains 1 RING-type zinc finger.

Database links:

Entrez Gene: 10293 Human

Omim: 605958 Human

SwissProt: Q9BWF2 Human

Unigene: 517972 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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