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Rabbit Anti-Plakophilin 3/Gold Conjugated antibody (bs-12703R-Gold)
訂購(gòu)熱線:400-901-9800
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說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12703R-Gold
英文名稱1 Rabbit Anti-Plakophilin 3/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的橋粒斑菲素蛋白3抗體
別    名 PKP 3 ; PKP3 ; PKP3_HUMAN ; Plakophilin 3b ; Plakophilin-3 ; Plakophilin3.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 87kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Plakophilin 3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

Function:
May play a role in junctional plaques.

Subcellular Location:
Nucleus. Cell junction > desmosome. Nuclear and associated with desmosomes.

Tissue Specificity:
Found in desmosomes of most simple and stratified epithelia. Not found in foreskin fibroblasts and various sarcoma-derived cell lines. Beside dendritic reticular cells of lymphatic follicles not found in non-epithelial desmosome-bearing tissues.

Similarity:
Belongs to the beta-catenin family.
Contains 8 ARM repeats.

Database links:

Entrez Gene: 11187 Human

Entrez Gene: 56460 Mouse

Entrez Gene: 293619 Rat

Omim: 605561 Human

SwissProt: Q9Y446 Human

SwissProt: Q9QY23 Mouse

Unigene: 534395 Human

Unigene: 350037 Mouse

Unigene: 144803 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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