| 產(chǎn)品編號 |
bs-4490R-Cy7 |
| 英文名稱1 |
Rabbit Anti-PLB1/Cy7 Conjugated antibody
|
| 中文名稱 |
Cy7標記的磷脂酶B1膜相關蛋白抗體 |
| 別 名 |
hPLB ;
Lysophospholipase ;
Phospholipase A2 ;
Phospholipase B ;
Phospholipase B/lipase ;
Phospholipase B1 ;
Phospholipase B1 membrane associated ;
PLB 1 ;
PLB ;
PLB/LIP. |
| 規(guī)格價格 |
100ul/2980元
購買 大包裝/詢價 |
| 說 明 書 |
100ul
|
| 研究領域 |
細胞生物 信號轉導 激酶和磷酸酶 |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應 |
(predicted: Human, Mouse, Rat, Cow, Sheep, )
|
| 產(chǎn)品應用 |
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
163kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human PLB1 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
PLB1 is a membrane-associated phospholipase which exhibits a calcium-independent broad substrate specificity including phospholipase A2/lysophospholipase activity. It shows preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. It also exhibits esterase activity toward p-nitrophenyl. It may act on the brush border membrane to facilitate the absorption of digested lipids.
Function:
Membrane-associated phospholipase. Exhibits a calcium-independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids (By similarity).
Subcellular Location:
Apical cell membrane; Single-pass type I membrane protein. Note: Present in the intestinal brush border membranes.
Tissue Specificity:
Expressed in the epidermis (at protein level).
Post-translational modifications:
Undergoes proteolytic cleavage in the ileum.
Similarity:
Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily.
Database links:
Entrez Gene: 151056 Human
Omim: 610179 Human
SwissProt: Q6P1J6 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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