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Rabbit Anti-Prokineticin 1/Gold Conjugated antibody (bs-23741R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@73327.net
訂購QQ:  400-901-9800
技術支持:techsupport@73327.net
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-23741R-Gold
英文名稱1 Rabbit Anti-Prokineticin 1/Gold Conjugated antibody
中文名稱 膠體金標記的內(nèi)分泌腺衍生血管內(nèi)皮生長因子抗體
別    名 Prokineticin-1/Endocrine-gland-derived vascular endothelial growth factor; Prokineticin1; Prokineticin 1; EG-VEGF; EG VEGF; EGVEGF; PROK1; EGVEGF; PK1; PRK1; PROK1_HUMAN; Black mamba toxin related protein; Endocrine gland derived vascular endothelial growth factor; Endocrine-gland-derived vascular endothelial growth factor; Mambakine; Prokineticin-1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 心血管  神經(jīng)生物學  信號轉導  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Mouse, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 9.7kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Prokineticin 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner. [provided by RefSeq, Sep 2011]

Function:
Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.

Subcellular Location:
Secreted.

Tissue Specificity:
Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta.

Similarity:
Belongs to the AVIT (prokineticin) family.

Database links:

Entrez Gene: 84432 Human

Entrez Gene: 246691 Mouse

Entrez Gene: 192205 Rat

Omim: 606233 Human

SwissProt: P58294 Human

SwissProt: Q14A28 Mouse

SwissProt: Q8R414 Rat

Unigene: 514793 Human

Unigene: 461353 Mouse

Unigene: 82757 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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